Police: NM teen charged in deaths of 2 adults, 3 children

By Daniel Arkin, Staff Writer, NBC News

Updated at 12:15 a.m. ET: A 15-year-old boy has been charged in the shooting deaths of two adults and three children in southwest Albuquerque, N.M., local police said.

The suspect, identified by Bernalillo County police as Nehemiah Griego, has been arrested and placed in a juvenile detention center. He is charged with two counts of murder and three counts of "child abuse resulting in death," according to a police statement.

A police statement identified the victims as?Greg Griego, 51, his wife, Sara Griego, 40, and three of their children -- Zephania Griego, 9, Jael Griego, 5, and Angelina Griego, 2.?

Greg Griego was a chaplain at the county jail in Albuquerque and spiritual counselor to the Albuquerque Fire Department, according to a statement by Fire Chief James Breen.?

Breen described Griego as dedicated and passionate chaplain with a "calming spirit and gentle nature." ?

Bernalillo County sheriff's deputies responded to a private residence in the city's South Valley area around 9:15 p.m. Saturday. They found the bodies inside the residence.

They also found several weapons at the scene of the crime,?including a semi-automatic military-style rifle, according to Bernalillo County sheriff's spokesman Aaron Williamson.

"There's no other way to say it, but we have a horrific crime scene we're working, and it'll be intensive, and we'll work hard to do everything that needs to be done," Sheriff Dan Houston told KRQE-TV.

The investigation is ongoing. It is unclear if the five victims were related to the suspect or each other, Williamson said.

NBC's Isolde Raftery contributed reporting.

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Source: http://usnews.nbcnews.com/_news/2013/01/20/16611914-police-new-mexico-teen-charged-in-deaths-of-two-adults-three-children?lite

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Epigenetics explains rheumatism? Genes and their regulatory 'tags' conspire to promote rheumatoid arthritis

Jan. 20, 2013 ? In one of the first genome-wide studies to hunt for both genes and their regulatory "tags" in patients suffering from a common disease, researchers have found a clear role for the tags in mediating genetic risk for rheumatoid arthritis (RA), an immune disorder that afflicts an estimated 1.5 million American adults. By teasing apart the tagging events that result from RA from those that help cause it, the scientists say they were able to spot tagged DNA sequences that may be important for the development of RA. And they suspect their experimental method can be applied to predict similar risk factors for other common, noninfectious diseases, like type II diabetes and heart ailments.

In a report published in Nature Biotechnology Jan. 20, the researchers at Johns Hopkins and the Karolinska Institutet say their study bridges the gap between whole-genome genetic sequencing and diseases that have no single or direct genetic cause. Most genetic changes associated with disease do not occur in protein-coding regions of DNA, but in their regulatory regions, explains Andrew Feinberg, M.D., M.P.H., a Gilman scholar, professor of molecular medicine and director of the Center for Epigenetics at the Johns Hopkins University School of Medicine's Institute for Basic Biomedical Sciences. "Our study analyzed both and shows how genetics and epigenetics can work together to cause disease," he says.

Rheumatoid arthritis is a debilitating disease that causes inflammation, stiffness, pain and disfigurement in joints, especially the small joints of the hands and feet. It is thought to be an autoimmune disease, meaning that the body's immune system attacks its own tissues, an assault led primarily by white blood cells. According to Feinberg, several DNA mutations are known to confer risk for RA, but there seem to be additional factors that suppress or enhance that risk. One probable factor involves chemical "tags" that attach to DNA sequences, part of a so-called epigenetic system that helps regulate when and how DNA sequences are "read," how they're used to create proteins and how they affect the onset or progress of disease.

To complicate matters, Feinberg notes, the attachment of the tags to particular DNA sequences can itself be regulated by genes. "The details of what causes a particular sequence to be tagged are unclear, but it seems that some tagging events depend on certain DNA sequences. In other words, those tagging events are under genetic control," he says. Other tagging events, however, seem to depend on cellular processes and environmental changes, some of which could be the result, rather than the cause, of disease.

To tease apart these two types of tagging events, the researchers catalogued DNA sequences and their tagging patterns in the white blood cells of more than 300 people with and without one form of RA.

The team then began filtering out the tags that did not appear to affect RA risk. For example, if tags were seen on the same DNA sequence in those with and without RA, it was assumed that the tags at those sites were irrelevant to the cause or development of the disease. Then, from among the RA-relevant tags, they narrowed in on tags whose placement seemed to be dependent on DNA sequence. Finally, they made sure that the DNA sequences identified were themselves more prevalent in patients with RA. In this way, they created a list of DNA sequences associated with altered DNA tagging patterns, both of which were associated with RA.

Ultimately, the team identified 10 DNA sites that were tagged differently in RA patients and whose tagging seemed to affect risk for RA. Nine of the 10 sites were within a region of the genome known to play an important role in autoimmune diseases, while the 10th was on a gene that had never before been associated with the disease. "Since RA is a disease in which the body's immune system turns on itself, current treatments often involve suppressing the entire immune system, which can have serious side effects," Feinberg says. "The results of this study may allow clinicians to instead directly target the culpable genes and/or their tags."

"Our method allows us to predict which tagging sites are most important in the development of a disease. In this study, we looked for tagging sites under genetic control, but similar tags can be triggered by environmental exposures, like smoking, so there are many applications for this type of work," says Yun Liu, Ph.D., a lead researcher on the project.

The study also may shed light on how evolution works, explains Feinberg. "It seems that natural selection might not simply be selecting for an individual's current fitness level but also for the adaptability of future generations given an unknown future. We think that certain genetic sequences may be biologically beneficial and conserved over time because they increase the amount of variation found in tagging patterns, giving individuals a greater chance of adapting to environmental changes."

Other authors of the report include Martin J. Aryee, M. Daniele Fallin, Arni Runarsson and Margaret Taub of the Johns Hopkins University School of Medicine; and Leonid Padyukov, Espen Hesselberg, Lovisa Reinius, Nathalie Acevedo, Marcus Ronninger, Lementy Shchetynsky, Annika Scheynius, Juha Kere, Lars Alfredsson, Lars Klareskog and Tomas J. Ekstr?m of the Karolinska Institutet, Sweden.

This work was supported by grants from the National Institutes of Health's Centers of Excellence in Genomic Science (5P50HG003233), the Swedish Research Council, the Swedish COMBINE project, the Swedish Foundation for Strategic Research, AFA Insurance and the European Research Council.

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Story Source:

The above story is reprinted from materials provided by Johns Hopkins Medicine.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Yun Liu, Martin J Aryee, Leonid Padyukov, M Daniele Fallin, Espen Hesselberg, Arni Runarsson, Lovisa Reinius, Nathalie Acevedo, Margaret Taub, Marcus Ronninger, Klementy Shchetynsky, Annika Scheynius, Juha Kere, Lars Alfredsson, Lars Klareskog, Tomas J Ekstr?m, Andrew P Feinberg. Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nature Biotechnology, 2013; DOI: 10.1038/nbt.2487

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/I0jgHEjY7vw/130120145813.htm

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Jaw Dropping (talking-points-memo)

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jahedaaos: Crafts At Home and Online | Bandage Blog

While we?re not exactly crafty individuals here, we definitely understand the value of crafts and other make-your-own hobbies. Between feeding creativity, improving coordination, and helping with concentration, crafts are great for individuals and bringing families together.

We?ve found two websites that provide craft and artisan ideas and classes, and they?re very affordable. They?re?Craftsy and Universal Class. These sites allow you to explore many different things to make yourself or take a class to learn how to.

Groupon provides deals for Craftsy every now and then, so make sure you check Groupon out if you?re interested in using Craftsy.

Universal Class actually provides more than 500 classes in many, many different subjects and fields. If crafts aren?t your cup of tea, there are many other options available, including cooking and even performing arts.

Our Make-Your-Own section in Idea Bandages also has several ideas for places to go to use and expand your creativity. Try something new. Sometimes something as simple as this can open you and your family to a whole new world and interest.

Have a wonderful weekend,

Family Bandage

Source: http://familybandage.wordpress.com/2013/01/18/crafts-at-home-and-online/

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Source: http://jahedaaos.blogspot.com/2013/01/crafts-at-home-and-online-bandage-blog.html

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The Next Kinect Will Turn Everyone Into a Jedi?Everywhere!

The video wants to make me rip my eyes off with the edge of my Xbox gamepad, but it heralds an immediate future that fires a clusterstorm of nerdgasms inside my sci-fi-damaged brain. It shows what Capri, the next 3D sensor by the makers of Microsoft Kinect, is bringing to us: extreme precision, fast motion tracking that gadget makers would be able to embed everywhere, from your tablet, laptop and TV to elevators, robots and appliances. It basically enables a future in which you are some kind of Jedi or wizard, casually waving your hand at things to make them work. More »

Source: http://feeds.gawker.com/~r/gizmodo/full/~3/7jomp-HS_ZU/the-next-kinect-will-turn-everyone-into-a-jedi

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Nikon Coolpix L810 camera with Smartest Features ever

Home | Arts & entertainment | Photography

Introduction:

It you secretly nurture a dream of photography, then the new Nikon Coolpix L810 is a must buy for you. It comes with power packed features that can encourage and enhance your photography experience. Like always Nikon has stood by its reputation of maintaining great balance of style with technology. No wonder its an undisputed leader in cameras for years. You are never confused while buying Nikon cameras, as you know you are picking nothing but the best. This is a common opinion of Nikon consumers over the years. This is due to sheer hard work of great minds and dedication of people at Nikon that has helped it to be where it is today.

The new Nikon Coolpix L810 is yet another jewel in the crown of Nikon that would shine for years. This high end digital camera comes with optical zoom of 26x, 16 megapixel camera with CCD sensor. An LCD screen of 3 inch to view your picture along with AA alkaline batteries. The new Nikon Coolpix L810 comes with an image processor of EXPEED C2 and a 720p HD video. This digital camera is ideal if photography is your passion and minute details in the photographs bring out the creative satisfaction in you. However saying this it doesn?t make it limited to photographers only. It?s a point and shoot digital camera, making it easy to use for amateurs too. The placements of the buttons are easy to access and conveniently placed. This camera is available in 4 vibrant colors, black, blue, red and bronze. If you are bored with black camera you can try a bronze or a red one that can be a welcome change. This is a must have accessory for any outdoor or indoor events.

The new Nikon Coolpix L810 is available at all the leading retail outlets near you. However if you find it difficult to travel and beat the traffic to reach your nearest retail store. You can order in online too. There are a number of online shopping portals that offer the new Nikon Coolpix L810 with attractive offers and can readily deliver it to your home with two to three days from ordering it online. If you have never ordered anything online before, do not be apprehensive, the pack would be sealed and would not be tampered. Most of the online shopping portals offer a 15 day return period if you are not happy with the product. The Nikon Coolpix L810 price is very affordable.

Online shopping is available for various products, from digital cameras, mobile phone, electronic goods and much more. You can pay through your credit or debit card or you can also pay by cash at the time of delivery. So don?t waste any more time. Check out online shopping portals today and buy your new Nikon Coolpix L810 before it gets out of stock.

About the Author

Devika is a budding freelance tech writer, gadget and Photography enthusiast, and social media junkie. She writes regularly about digital camera and has been written several articles on nikon digital cameras & fujifilm sl300.

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Japan probe suspects excess voltage in 787 battery

U.S. officials, center, inspect a All Nippon Airways jet which made an emergency landing Wednesday, at Takamatsu airport in Takamatsu, western Japan, Friday, Jan. 18, 2013. An official with Japan?s transport safety board says four U.S. officials, including two Boeing Co. representatives, have arrived at the airport in western Japan to inspect the troubled Boeing 787 jet. (AP Photo/Kyodo News) JAPAN OUT, MANDATORY CREDIT, NO LICENSING IN CHINA, HONG KONG, JAPAN, SOUTH KOREA AND FRANCE

U.S. officials, center, inspect a All Nippon Airways jet which made an emergency landing Wednesday, at Takamatsu airport in Takamatsu, western Japan, Friday, Jan. 18, 2013. An official with Japan?s transport safety board says four U.S. officials, including two Boeing Co. representatives, have arrived at the airport in western Japan to inspect the troubled Boeing 787 jet. (AP Photo/Kyodo News) JAPAN OUT, MANDATORY CREDIT, NO LICENSING IN CHINA, HONG KONG, JAPAN, SOUTH KOREA AND FRANCE

This Jan. 17, 2013 photo provided by the Japan Transport Safety Board shows the distorted main lithium-ion battery of the All Nippon Airways' Boeing 787 which made an emergency landing on Wednesday, Jan. 16, 2013 at Takamatsu airport in Takamatsu, western Japan. U.S. safety officials and Boeing inspectors joined a Japanese investigation Friday into the 787 jet at the center of a worldwide grounding of the technologically advanced aircraft. The pilot of the ANA plane made an emergency landing Wednesday morning after he smelled something burning and received a cockpit warning of battery problems. All passengers evacuated the plane on emergency slides. (AP Photo/Japan Transport Safety Board) EDITORIAL USE ONLY, NO SALES

This Jan. 17, 2013 photo provided by the Japan Transport Safety Board shows the distorted main lithium-ion battery and its lid, left, of the All Nippon Airways' Boeing 787 which made an emergency landing on Wednesday, Jan. 16, 2013 at Takamatsu airport in Takamatsu, western Japan. At right are the model in normal condition. U.S. safety officials and Boeing inspectors joined a Japanese investigation Friday into the 787 jet at the center of a worldwide grounding of the technologically advanced aircraft. The pilot of the ANA plane made an emergency landing Wednesday morning after he smelled something burning and received a cockpit warning of battery problems. All passengers evacuated the plane on emergency slides. (AP Photo/Japan Transport Safety Board) EDITORIAL USE ONLY, NO SALES

A representative of the U.S. investigation team is surrounded by the reporters as they arrived at Takamatsu airport, following an emergency landing of a Boeing 787 exposed a battery fire risk in Takamatsu, western Japan, Friday, Jan. 18, 2013. Boeing, the U.S. National Transportation Safety Board and Federal Aviation Administration were sending representatives to work with the Japanese government on the investigation, NTSB spokeswoman Kelly Nantel said. (AP Photo/Kyodo News) JAPAN OUT, MANDATORY CREDIT, NO LICENSING IN CHINA, HONG KONG, JAPAN, SOUTH KOREA AND FRANCE

Representatives of the U.S. investigation team arrive at Takamatsu airport, to investigate an emergency landing of a Boeing 787 which exposed a battery fire risk in Takamatsu, western Japan, Friday, Jan. 18, 2013. Boeing, the U.S. National Transportation Safety Board and Federal Aviation Administration were sending representatives to work with the Japanese government on the investigation, NTSB spokeswoman Kelly Nantel said. (AP Photo/Kyodo News) JAPAN OUT, MANDATORY CREDIT, NO LICENSING IN CHINA, HONG KONG, JAPAN, SOUTH KOREA AND FRANCE

TOKYO (AP) ? The burned insides of a battery in the Boeing 787 at the center of a worldwide grounding of the aircraft indicate it operated at a voltage above its design limit, a Japanese investigator said Friday, as U.S. officials joined Japan's probe into the incident.

The All Nippon Airways plane made an emergency landing Wednesday morning in western Japan after its pilots smelled something burning and received a cockpit warning of battery problems. Nearly all 50 of the 787s in use around the world have since been grounded.

Photos provided by the Japan Transport Safety Board of the lithium ion battery that was located beneath the 787's cockpit show a blackened mass of wires and other components within a distorted blue casing.

Japan transport ministry investigator Hideyo Kosugi said the state of the battery indicated "voltage exceeding the design limit was applied" to it.

He said the similarity of the burned insides of the battery from the ANA flight to the battery in a Japan Airlines 787 that caught fire Jan. 7 while the jet was parked at Boston's Logan International Airport suggested a common cause.

"If we compare data from the latest case here and that in the U.S., we can pretty much figure out what happened," Kosugi said.

The 787 relies more than any other modern airliner on electrical signals to help power nearly everything the plane does. It's also the first Boeing plane to use rechargeable lithium-ion batteries for its main electrical system. Such batteries are prone to overheating and have additional safeguards installed that are meant to control the problem and prevent fires.

GS Yuasa Corp., the maker of the lithium-ion batteries used in the 787s, said Thursday it was helping with the investigation but that the cause of the problem was unclear. It said the problem could be the battery, the power source or the electronics system.

U.S. safety officials and Boeing inspectors joined the Japan Transport Safety Board investigation Friday.

The American investigators ? one each from the Federal Aviation Administration and the National Transportation Safety Board and two from Boeing Co. ? inspected the ANA jet on the tarmac at Takamatsu airport in western Japan.

An initial inspection by Japanese officials of the 787 found that a flammable battery fluid known as electrolyte had leaked from the plane's main lithium-ion battery beneath the cockpit. It also found burn marks around the battery.

Aviation authorities in Japan have directed ANA, which owns 17 of the planes, and Japan Airlines, with seven, not to fly the jets until questions over their safety have been resolved.

The 787, known as the Dreamliner, is Boeing's newest jet, and the company is counting heavily on its success. Since its launch after delays of more than three years, the plane has been plagued by a series of problems.

The FAA has required U.S. carriers to stop flying 787s until the batteries are demonstrated to be safe. United Airlines has six of the jets and is the only U.S. carrier flying the model.

Aviation authorities in other countries usually follow the lead of the country where the manufacturer is based.

___

Associated Press writer Mari Yamaguchi contributed.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-01-18-Japan-Boeing%20787/id-ab879394653440508a3ef14bb6a1177d

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